The Binding of Isaac: Rebirth

"When Isaac’s mother starts hearing the voice of God demanding a sacrifice be made to prove her faith, Isaac escapes into the basement, where he faces droves of deranged enemies, lost brothers and sisters, his fears and eventually his mother. Gameplay
The Binding of Isaac: Rebirth is the randomly generated action RPG shooter that started the new roguelike era. Following Isaac on his journey, players will find bizarre treasures that change Isaac’s form, giving him superhuman abilities and enabling him to battle droves of mysterious creatures, discover secrets and fight his way to safety.

Key Features:
Over 500 hours of gameplay
4 BILLION Seeded runs!
20 Challenge runs
450+ items
Integrated controller support for popular control pads
Analog directional movement and speed
Tons of feature film-quality animated endings
Over 100 specialized seeds
2-player local co-op
Over 100 co-op characters
Dynamic lighting, visual effects and art direction
Multiple Save slots
Poop physics!
A bunch of achievements
The ultimate roguelike

Uber secrets including:
10 Playable Characters
100+ enemies
Over 50 bosses
Mystic Runes
Upgradeable shops
Rooms FULL OF POOP!"